DNA App Spotlight: Heart Health, Inflammation & Essential Minerals

This spotlight covers three health-focused DNA apps available in the Partner Marketplace, covering cardiovascular health, inflammation, and essential vitamins and minerals.

App Spotlight 1: Cardiovascular Health

Heart disease and its related complications are among the top causes of early death in many countries. Your genetic makeup plays a significant role in how your body handles cardiovascular stress, and your genes directly impact your risk of developing certain cardiovascular diseases.

Eating a healthy diet, exercising regularly, and avoiding smoking are all ways to improve cardiovascular health. But for those who are genetically predisposed to a higher risk of heart or vascular disease, lifestyle changes alone may not be enough. Understanding your genetic risk is an important first step.

The Cardiovascular Health report analyzes your genome to help you understand your risks and take steps to prevent serious adverse health outcomes. Inside the report, you will find insights on:

• Genetic risk factors for coronary artery disease and heart attack
• Cholesterol and lipid metabolism markers
• Blood pressure and hypertension predispositions
• Arrhythmia and cardiac rhythm risk factors
• Personalized lifestyle and dietary recommendations based on your cardiovascular genetic profile

App Spotlight 2: Inflammation And Immunity

Millions of people around the world are affected by inflammation and associated conditions, ranging from mild seasonal allergies to chronic conditions like asthma and arthritis. Inflammation is part of your body's immune response system, and your genetics play a significant role in how it works.

Genes like APOC1, PABPC4, and HBB detect inflammation signals. Others like HNFA1 and CR1 promote the inflammation response. And genes like HNF4A and SLC22A5 are responsible for reducing inflammation. Understanding your personal genetic inflammation profile can help you identify triggers and manage risk more effectively.

The Inflammation And Immunity report analyzes 96 different genetic markers to provide insights including:

• Your genetic predisposition to chronic inflammation
• Immune system response patterns and triggers
• Risk factors for inflammation-related conditions including allergies, asthma, and arthritis
• Personalized dietary and lifestyle recommendations to help manage inflammation

App Spotlight 3: Vitamins DNA

Essential minerals and vitamins are chemical compounds that your body needs to sustain life but cannot produce itself. Minerals like sodium, calcium, zinc, iron, and potassium perform critical roles in your body's ecosystem. Deficiencies in essential nutrients can lead to serious health disorders, especially over the long term.

Eating a healthy, balanced diet is the obvious first step in maintaining nutritional health. But if you are genetically predisposed to a deficiency, you may need to do more to stay healthy. For example, a genetic predisposition to low Vitamin D levels can in turn affect calcium absorption, and together these deficiencies can contribute to osteoporosis later in life.

The Vitamins DNA report helps you understand and manage your genetic risk of essential nutrient deficiencies, so you can take action before deficiencies become a problem. The report covers:

• Genetic predispositions to deficiencies in key vitamins including Vitamin D, B12, and folate
• Essential mineral absorption and metabolism markers including calcium, iron, and zinc
• Personalized supplement and dietary recommendations based on your nutrient genetic profile

How to Access These Reports

If you have already taken a DNA test from 23andMe, AncestryDNA, MyHeritage, or another provider, you can upload your raw DNA data to Sequencing for free and run any of these reports from the Partner Marketplace. For the most complete analysis, Sequencing offers clinical grade whole genome sequencing that reads 100% of your DNA across all of your over 30,000 genes.